CBS has the multi-million dollar challenge of replacing the ratings and revenue lost by their apparent cancellation of "Two & A Half Men" following the well publicized (and escalating) difficulties surrounding star Charlie Sheen. E! has reported that producers had reached out to John Stamos to replace Charlie and keep the show on the air. However, John says he's not replacing Charlie, although he did tweet a clever response to the questions.

"Contrary to the rumors, I am not replacing Charlie Sheen on Two and a Half Men. However, Martin Sheen has asked me to be his son."

Details from E! Online here.